Mpigi district located in the Buganda sub-region, it borders the districts of Wakiso in the North East and East, Mityana in the North, Butambala in West and North West, Kalangala and Lake Victoria in the South and Kalungu is to the south West. At Independence in 1962, Mpigi was part of Buganda Kingdom. Following the abolition of kingdoms in 1967, Buganda was divided into 4 districts-East Mengo, West Mengo, Mubende and Masaka districts. Under the 1974 provincial Administration, West Mengo became Mengo District, which in 1980 became Mpigi District. In 2000, Busiro and Kyadondo counties and Entebbe Municipality were separated from it to create Wakiso District.
As of 2014, the district has a total of 250,548 people and the main language in this district is Luganda.
The district is primarily rural and the ethnic make-up of the district consists mostly of baganda farmers and another development, through the Uganda National Oil Company (UNOC), the government secured 299 acres of land at Namwambula Village in Mpigi where it intends to build a storage terminal, which will host a 60-million litre storage facility for petroleum products.
Mpigi district harbors the Equator, a natural spectacular phenomena that traverses district at Nabusanke in Nkozi sub-county and River Katonga One of Uganda’s longest rivers that Joins Lake Victoria to Lake George traverses the district in Nkozi Sub County and also to mention Mpanga Eco Tourism site, Katebo Crocodile Site, Cultural Sites (Kibuuka Omumbaale and Buganda Clan sites, Namirembe cultural site).